A recent study published in the Journal of the American Medical Association (JAMA) shows that a simple supplement, administered alongside a well-known medication, can make a real difference in preventing strokes. The results come from extensive research conducted in China, involving a sample of over 20,000 people with hypertension.
Participants had not previously suffered strokes but had elevated blood pressure levels. Half of them received standard treatment with enalapril, an enzyme inhibitor commonly used to control blood pressure. The other half followed a regimen that included, in addition to enalapril, 0.8 mg of folic acid, also known as vitamin B9.
The results are clear: the group that received vitamin B9 had a significantly lower risk of stroke—2.7% of them suffered a stroke, compared to 3.4% in the group that received only enalapril. Additionally, cardiovascular mortality was reduced by nearly one percentage point.
What exactly does vitamin B9 do?
Folic acid is involved in the production of blood cells, the formation of DNA, and the proper functioning of the nervous system. Although it is primarily known for its role during pregnancy, the new study highlights another important benefit: protection against strokes.
The mechanism is related to homocysteine, a compound that, in large quantities, can affect blood vessels. Vitamin B9 helps maintain this compound within normal limits, thereby reducing the risk of inflammation and clot formation.
Where can you get vitamin B9 if you don’t want supplements?
The natural form of the vitamin is called folate and is found in many accessible foods:
- Green leafy vegetables such as spinach, broccoli, and kale
- Beans and lentils rich not only in folic acid but also in fiber
- Citrus fruits and natural juices oranges are among the best sources
- Asparagus, avocado, and beets
- Beef liver a concentrated source, but should be consumed in moderation
- Whole grains especially if they are not industrially processed
Can folic acid replace hypertension treatment?
No. The study does not recommend discontinuing prescribed medications. Instead, it provides arguments in favor of including vitamin B9 in the therapeutic strategy for patients with elevated blood pressure, especially if there is a risk of stroke.
Dr. Yong Huo, the lead author of the research, states that the benefits are evident and that this combination could be applied on a large scale without significant additional costs to the healthcare system.
When does supplementation become a good option?
- If you have hypertension and a family history of strokes or heart attacks
- If you are undergoing treatment with ACE inhibitors (such as enalapril) and have a diet low in green vegetables
- If you are over 50 and want to reduce cardiovascular risks
What do experts say about prevention?
Alongside medication treatments, lifestyle remains essential. Drastic changes are not necessary. A varied diet with whole and plant-based foods, regular exercise, and regular medical monitoring can make a difference. Vitamin B9, whether from diet or as a supplement, complements this picture.
